Recommendations | Class | Level |
iFR/FFR to identify hemodynamically relevant coronary lesion(s) in stable patients when evidence of ischemia is not available | I | A |
FFR-guided PCI in patients with multivessel disease. | IIa | B |
DEFINE PCI:
Unseen focal lesions cause residual ischemia
The DEFINE PCI study used iFR pullback to understand the rate and causes of residual ischemia in 500 patients undergoing contemporary PCI. Early results find that residual ischemia is common, and causes are treatable.13
Angiographically focal stenosis defined as ≤ 15 mm.13
DEFINE PCI – experts discuss the key finding
Allen Jeremias discusses: DEFINE PCI
Philips provides you with the opportunity to use iFR which is the only clinically validated resting index (recommended by AHA and SCAI) along with FFR. In 2017 Davies et al. and Götberg et al. validated the non-inferiority of iFR compared to FFR .
FFR = Distal Coronary Pressure (Pd) (During maximal hyperemia)
iFR = Distal Coronary Pressure (Pd) (During wave-free period)
FFR A physiology index to determine the functional significance of coronary stenosis. FFR is the ratio of the distal pressure compared to the proximal pressure during maximal blood flow (hyperemia), which can be induced by injecting products such as adenosine or papaverine.
iFR
In-depth information for lesion specific ischemia
The Cardiovascular Center of Catania prefers to use
Watch a case study on the LAD with diffuse disease
Davide Capodanno MD and Alessio La Manna MD, practicing interventional cardiologists at
Sen
“In this study, we have clearly demonstrated that it is safe to defer on the basis of iFR. If I see a patient with
Dr. Sayan Sen, Consultant Cardiologist, Hammersmith Hospital & Imperial College London, discusses details of the LAD sub-study of DEFINE-FLAIR
Study aims
iFR and FFR results
Value of
You are about to visit a Philips global content page
ContinueYou are about to visit the Philips USA website.
I understand